Protein Modification Reagents
Medchemexpress LLC Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 TFA | 2435572-49-7 | 99.28% | 648.58 | 50 MG
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form usually boasts enhanced water solubility and stability.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates thalidomide based cereblon ligand
- Features a 3-unit PEG linker for PROTAC technology
- Salt form offers enhanced water solubility and stability
- For research use only
Medchemexpress LLC Aminooxy-PEG2-azide | 1043426-13-6 | ≥96.0% | 190.20 | 25 MG
Aminooxy-PEG2-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs and serves as a non-cleavable 2-unit PEG ADC linker for synthesizing antibody-drug conjugates (ADCs). This compound is a click chemistry reagent, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- Utilized in the synthesis of PROTACs
- Serves as a non-cleavable 2-unit PEG ADC linker for antibody-drug conjugates
- Click chemistry reagent containing an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition reactions
- Participates in strain-promoted alkyne-azide cycloaddition reactions
Medchemexpress LLC DBCO-PEG24-NHS ester | 2765066-38-2 | C74H119N3O30 | 25 MG
DBCO-PEG24-NHS ester is a click chemistry reagent that reacts specifically and efficiently with primary amines under neutral or slightly basic conditions to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long, flexible connection, minimizing steric hindrance during ligation. DBCO is commonly used for copper-free click chemistry reactions.
- Contains an NHS ester for covalent bond formation
- Enhances water solubility
- Minimizes steric hindrance during ligation
- Suitable for copper-free click chemistry reactions
Medchemexpress LLC Aminooxy-PEG2-azide | 1043426-13-6 | ≥96.0% | 190.20 | 250 MG
Aminooxy-PEG2-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs and as a non-cleavable 2-unit PEG ADC linker for antibody-drug conjugates. It functions as a click chemistry reagent with an Azide group.
- Enables copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing alkyne groups.
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Utilized in the synthesis of PROTACs.
- Employed in the synthesis of antibody-drug conjugates (ADCs).
Supply Solutions Sigma Aldrich - Collagenase B, 2.5g, non-sterile * Third Party Item
Sigma Aldrich - Collagenase B, 2.5g, non-sterile * Third Party Item
Medchemexpress LLC PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 40:60) | 95.0% | 20kDA to 5.0kDA | 50 MG
PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 40:60) is a type of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. It has a molecular weight range of 20kDA to 5.0kDA and contains a 40:60 ratio of lactic acid (LA) to glycolic acid (GA) molecules.
- It is a nanoparticle.
- For research use only.
- Appearance: solid
- Color: white to off-white
ABclonal Technology SREK1 Rabbit pAb
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.